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Purpurolide C-based microneedle promotes macrophage-mediated diabetic wound healing via inhibiting TLR4-MD2 dimerization and MYD88 phosphorylation

Delayed wound healing in diabetes is a global challenge, and the development of related drugs is a clinical problem to be solved. In this study, purpurolide C (PC), a small-molecule secondary metabolite of the endophytic fungus Penicillium purpurogenum, was found to promote diabetic wound healing. T...

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Detalles Bibliográficos
Autores principales:	Liu, Yitong, Xia, Guiyang, Chen, Yingyi, Xia, Huan, Xu, Junji, Guo, Lijia, Lin, Sheng, Liu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692347/ https://www.ncbi.nlm.nih.gov/pubmed/38045060 http://dx.doi.org/10.1016/j.apsb.2023.05.032

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