ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells

Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with an immunosuppressive tumor microenvironment (TME). In this environment, myeloid cells, such as myeloid-derived suppressor cells (MDSCs), play a pivotal role in suppressing antitumor immunity. Lipometabolism is closely related to t...

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Detalles Bibliográficos
Autores principales: Wang, Mingjin, Wang, Weida, You, Shen, Hou, Zhenyan, Ji, Ming, Xue, Nina, Du, Tingting, Chen, Xiaoguang, Jin, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692383/
https://www.ncbi.nlm.nih.gov/pubmed/38045043
http://dx.doi.org/10.1016/j.apsb.2023.09.005

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