Non-canonical STING–PERK pathway dependent epigenetic regulation of vascular endothelial dysfunction via integrating IRF3 and NF-κB in inflammatory response

Inflammation-driven endothelial dysfunction is the major initiating factor in atherosclerosis, while the underlying mechanism remains elusive. Here, we report that the non-canonical stimulator of interferon genes (STING)–PKR-like ER kinase (PERK) pathway was significantly activated in both human and...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xuesong, Chen, Xiang, Zheng, Longbin, Chen, Minghong, Zhang, Yunjia, Zhu, Ruigong, Chen, Jiajing, Gu, Jiaming, Yin, Quanwen, Jiang, Hong, Wu, Xuan, Ji, Xian, Tang, Xin, Dong, Mengdie, Li, Qingguo, Gao, Yuanqing, Chen, Hongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692388/
https://www.ncbi.nlm.nih.gov/pubmed/38045042
http://dx.doi.org/10.1016/j.apsb.2023.08.015

Ejemplares similares

Ejemplares similares