Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia

Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected...

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Detalles Bibliográficos
Autores principales: Banerjee, Mainak, Mukhopadhyay, Pradip, Basu, Madhurima, Ghosh, Sujoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692405/
https://www.ncbi.nlm.nih.gov/pubmed/38045663
http://dx.doi.org/10.15605/jafes.038.02.21
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author Banerjee, Mainak
Mukhopadhyay, Pradip
Basu, Madhurima
Ghosh, Sujoy
author_facet Banerjee, Mainak
Mukhopadhyay, Pradip
Basu, Madhurima
Ghosh, Sujoy
author_sort Banerjee, Mainak
collection PubMed
description Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected by corneal confocal microscopy in an objective easy-to-perform non-invasive test might be a surrogate indicator of underlying autonomic dysfunction in T1DM and IAH.
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spelling pubmed-106924052023-12-03 Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia Banerjee, Mainak Mukhopadhyay, Pradip Basu, Madhurima Ghosh, Sujoy J ASEAN Fed Endocr Soc Case Report Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected by corneal confocal microscopy in an objective easy-to-perform non-invasive test might be a surrogate indicator of underlying autonomic dysfunction in T1DM and IAH. Journal of the ASEAN Federation of Endocrine Societies 2023-07-15 2023 /pmc/articles/PMC10692405/ /pubmed/38045663 http://dx.doi.org/10.15605/jafes.038.02.21 Text en © 2023 Journal of the ASEAN Federation of Endocrine Societies https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
spellingShingle Case Report
Banerjee, Mainak
Mukhopadhyay, Pradip
Basu, Madhurima
Ghosh, Sujoy
Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title_full Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title_fullStr Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title_full_unstemmed Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title_short Corneal Confocal Microscopy Identifies Structural Small Fibre Abnormalities in an Adolescent with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
title_sort corneal confocal microscopy identifies structural small fibre abnormalities in an adolescent with type 1 diabetes and impaired awareness of hypoglycaemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692405/
https://www.ncbi.nlm.nih.gov/pubmed/38045663
http://dx.doi.org/10.15605/jafes.038.02.21
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