Langerhans Cell Histiocytosis Presenting as Anterior Neck Mass in a Child: A Case Report*

Thyroid involvement in Langerhans Cell Histiocytosis (LCH) is rare. We report a 10-year-old Filipino male who presented with a rapidly enlarging goiter. Computed tomography scan showed thyroid and bilateral submandibular masses with malignant features, pulmonary blebs and hepatic cysts. Ultrasound-g...

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Detalles Bibliográficos
Autores principales: Betansos, Kristine Mae, Cachero, Melissa Joyanne, Santos, Caridad, Fernandez, Eve, Mabulac, Marichu, Abad, Lorna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the ASEAN Federation of Endocrine Societies 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692419/
https://www.ncbi.nlm.nih.gov/pubmed/38045678
http://dx.doi.org/10.15605/jafes.038.02.15
Descripción
Sumario:Thyroid involvement in Langerhans Cell Histiocytosis (LCH) is rare. We report a 10-year-old Filipino male who presented with a rapidly enlarging goiter. Computed tomography scan showed thyroid and bilateral submandibular masses with malignant features, pulmonary blebs and hepatic cysts. Ultrasound-guided core needle biopsy findings were consistent with LCH and chemotherapy was initiated. This case demonstrates that LCH should be considered in patients with goiter. Multidisciplinary management is warranted to achieve proper diagnosis and institute timely treatment.

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