Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report

Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neural...

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Detalles Bibliográficos
Autores principales: Akkus, Sema, Amatya, Suban, Shrestha, Kriti, Sriwastava, Shitiz, Karides, Demetrios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692462/
https://www.ncbi.nlm.nih.gov/pubmed/38046926
http://dx.doi.org/10.1016/j.radcr.2023.10.032
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author Akkus, Sema
Amatya, Suban
Shrestha, Kriti
Sriwastava, Shitiz
Karides, Demetrios A.
author_facet Akkus, Sema
Amatya, Suban
Shrestha, Kriti
Sriwastava, Shitiz
Karides, Demetrios A.
author_sort Akkus, Sema
collection PubMed
description Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes.
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spelling pubmed-106924622023-12-03 Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report Akkus, Sema Amatya, Suban Shrestha, Kriti Sriwastava, Shitiz Karides, Demetrios A. Radiol Case Rep Case Report Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes. Elsevier 2023-11-17 /pmc/articles/PMC10692462/ /pubmed/38046926 http://dx.doi.org/10.1016/j.radcr.2023.10.032 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Akkus, Sema
Amatya, Suban
Shrestha, Kriti
Sriwastava, Shitiz
Karides, Demetrios A.
Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title_full Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title_fullStr Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title_full_unstemmed Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title_short Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
title_sort late-onset parry-romberg syndrome with atypical neurological manifestations: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692462/
https://www.ncbi.nlm.nih.gov/pubmed/38046926
http://dx.doi.org/10.1016/j.radcr.2023.10.032
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