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TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion

A crucial requirement for metastasis formation in ovarian high-grade serous carcinoma (HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems of primary human cells, we discovered that tumor-associated NK cells induce TRAIL-dependent apoptosis in mesothelial cells...

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Detalles Bibliográficos
Autores principales:	Steitz, Anna Mary, Schröder, Clarissa, Knuth, Isabel, Keber, Corinna U., Sommerfeld, Leah, Finkernagel, Florian, Jansen, Julia M., Wagner, Uwe, Müller-Brüsselbach, Sabine, Worzfeld, Thomas, Huber, Magdalena, Beutgen, Vanessa M., Graumann, Johannes, Pogge von Strandmann, Elke, Müller, Rolf, Reinartz, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692662/ https://www.ncbi.nlm.nih.gov/pubmed/38047087 http://dx.doi.org/10.1016/j.isci.2023.108401

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