Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

Cytotoxin-associated gene A (CagA) of Helicobacter pylori (Hp) may promote immune evasion of Hp-infected gastric cancer (GC), but potential mechanisms are still under explored. In this study, the positive rates of CagA and PD-L1 protein in tumor tissues and the high level of exosomal PD-L1 protein i...

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Detalles Bibliográficos
Autores principales: Wang, Jinfeng, Deng, Rilin, Chen, Shuai, Deng, Shun, Hu, Qi, Xu, Biaoming, Li, Junjun, He, Zhuo, Peng, Mingjing, Lei, Sanlin, Ma, Tiexiang, Chen, Zhuo, Zhu, Haizhen, Zuo, Chaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692710/
https://www.ncbi.nlm.nih.gov/pubmed/38047083
http://dx.doi.org/10.1016/j.isci.2023.108414

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