Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen

Hypoxic responses in plants involve Plant Cysteine Oxidases (PCOs). They catalyze the N-terminal cysteine oxidation of Ethylene Response Factors VII (ERF-VII) in an oxygen-dependent manner, leading to their degradation via the cysteine N-degron pathway (Cys-NDP) in normoxia. In hypoxia, PCO activity...

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Detalles Bibliográficos
Autores principales: Lavilla-Puerta, Mikel, Latter, Rebecca, Bellè, Francesca, Cervelli, Tiziana, Galli, Alvaro, Perata, Pierdomenico, Chini, Andrea, Flashman, Emily, Giuntoli, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692734/
https://www.ncbi.nlm.nih.gov/pubmed/37863264
http://dx.doi.org/10.1016/j.jbc.2023.105366

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