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The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling

Legionella pneumophila is an environmental bacterium, which replicates in amoeba but also in macrophages, and causes a life-threatening pneumonia called Legionnaires’ disease. The opportunistic pathogen employs the α-hydroxy-ketone compound Legionella autoinducer-1 (LAI-1) for intraspecies and inter...

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Detalles Bibliográficos
Autores principales: Fan, Mingzhen, Kiefer, Patrick, Charki, Paul, Hedberg, Christian, Seibel, Jürgen, Vorholt, Julia A., Hilbi, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692735/
https://www.ncbi.nlm.nih.gov/pubmed/37866633
http://dx.doi.org/10.1016/j.jbc.2023.105376