AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss

Osteoclasts are specialized cells responsible for bone resorption, a highly energy-demanding process. Focus on osteoclast metabolism could be a key for the treatment of osteolytic diseases including osteoporosis. In this context, AMP-activated protein kinase α1 (AMPKα1), an energy sensor highly expr...

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Detalles Bibliográficos
Autores principales: Ribeiro, Mariana S.P., Venturini, Lucas G.R., Speck-Hernandez, Cesar A., Alabarse, Paulo V.G., Xavier, Thais, Taira, Thaise M., Duffles, Letícia F., Cunha, Fernando Q., Fukada, Sandra Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692901/
https://www.ncbi.nlm.nih.gov/pubmed/37871745
http://dx.doi.org/10.1016/j.jbc.2023.105379

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