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SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum

Nsp3s are the largest nonstructural proteins of coronaviruses. These transmembrane proteins include papain-like proteases (PLpros) that play essential roles in cleaving viral polyproteins into their mature units. The PLpro of SARS-CoV viruses also have deubiquitinating and deISGylating activities. A...

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Detalles Bibliográficos
Autores principales:	Yang, Mei, Mariano, Jennifer, Su, Rebecca, Smith, Christopher E., Das, Sudipto, Gill, Catherine, Andresson, Thorkell, Loncarek, Jadranka, Tsai, Yien Che, Weissman, Allan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692909/ https://www.ncbi.nlm.nih.gov/pubmed/37838170 http://dx.doi.org/10.1016/j.jbc.2023.105346

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