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Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams

BACKGROUND AND PURPOSE: Accurate dosimetry in Ultra-High Dose Rate (UHDR) beams is challenging because high levels of ion recombination occur within ionisation chambers used as reference dosimeters. A Small-body Portable Graphite Calorimeter (SPGC) exhibiting a dose-rate independent response was bui...

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Autores principales: Cotterill, John, Flynn, Sam, Thomas, Russell, Subiel, Anna, Lee, Nigel, Shipley, David, Palmans, Hugo, Lourenço, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692912/
https://www.ncbi.nlm.nih.gov/pubmed/38045641
http://dx.doi.org/10.1016/j.phro.2023.100506
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author Cotterill, John
Flynn, Sam
Thomas, Russell
Subiel, Anna
Lee, Nigel
Shipley, David
Palmans, Hugo
Lourenço, Ana
author_facet Cotterill, John
Flynn, Sam
Thomas, Russell
Subiel, Anna
Lee, Nigel
Shipley, David
Palmans, Hugo
Lourenço, Ana
author_sort Cotterill, John
collection PubMed
description BACKGROUND AND PURPOSE: Accurate dosimetry in Ultra-High Dose Rate (UHDR) beams is challenging because high levels of ion recombination occur within ionisation chambers used as reference dosimeters. A Small-body Portable Graphite Calorimeter (SPGC) exhibiting a dose-rate independent response was built to offer reduced uncertainty on secondary standard dosimetry in UHDR regimes. The aim of this study was to quantify the effect of the geometry and material properties of the device on the dose measurement. MATERIALS AND METHODS: A detailed model of the SPGC was built in the Monte Carlo code TOPAS (v3.6.1) to derive the impurity and gap correction factors, [Formula: see text] and [Formula: see text]. A dose conversion factor, [Formula: see text] , was also calculated using FLUKA (v2021.2.0). These factors convert the average dose to its graphite core to the dose-to-water for a 249.7 MeV mono-energetic spot-scanned clinical proton beam. The effect of the surrounding Styrofoam on the dose measurement was examined in the simulations by substituting it for graphite. RESULTS: The [Formula: see text] and [Formula: see text] correction factors were 0.9993 ± 0.0002 and 1.0000 ± 0.0001, respectively when the Styrofoam was not substituted, and 1.0037 ± 0.0002 and 0.9999 ± 0.0001, respectively when substituted for graphite. The dose conversion factor was calculated to be 1.0806 ± 0.0001. All uncertainties are Type A. CONCLUSIONS: Impurity and gap correction factors, and the dose conversion factor were calculated for the SPGC in a FLASH proton beam. Separating out the effect of scatter from Styrofoam insulation showed this as the dominating correction factor, amounting to 1.0043 ± 0.0002.
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spelling pubmed-106929122023-12-03 Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams Cotterill, John Flynn, Sam Thomas, Russell Subiel, Anna Lee, Nigel Shipley, David Palmans, Hugo Lourenço, Ana Phys Imaging Radiat Oncol Original Research Article BACKGROUND AND PURPOSE: Accurate dosimetry in Ultra-High Dose Rate (UHDR) beams is challenging because high levels of ion recombination occur within ionisation chambers used as reference dosimeters. A Small-body Portable Graphite Calorimeter (SPGC) exhibiting a dose-rate independent response was built to offer reduced uncertainty on secondary standard dosimetry in UHDR regimes. The aim of this study was to quantify the effect of the geometry and material properties of the device on the dose measurement. MATERIALS AND METHODS: A detailed model of the SPGC was built in the Monte Carlo code TOPAS (v3.6.1) to derive the impurity and gap correction factors, [Formula: see text] and [Formula: see text]. A dose conversion factor, [Formula: see text] , was also calculated using FLUKA (v2021.2.0). These factors convert the average dose to its graphite core to the dose-to-water for a 249.7 MeV mono-energetic spot-scanned clinical proton beam. The effect of the surrounding Styrofoam on the dose measurement was examined in the simulations by substituting it for graphite. RESULTS: The [Formula: see text] and [Formula: see text] correction factors were 0.9993 ± 0.0002 and 1.0000 ± 0.0001, respectively when the Styrofoam was not substituted, and 1.0037 ± 0.0002 and 0.9999 ± 0.0001, respectively when substituted for graphite. The dose conversion factor was calculated to be 1.0806 ± 0.0001. All uncertainties are Type A. CONCLUSIONS: Impurity and gap correction factors, and the dose conversion factor were calculated for the SPGC in a FLASH proton beam. Separating out the effect of scatter from Styrofoam insulation showed this as the dominating correction factor, amounting to 1.0043 ± 0.0002. Elsevier 2023-11-08 /pmc/articles/PMC10692912/ /pubmed/38045641 http://dx.doi.org/10.1016/j.phro.2023.100506 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Cotterill, John
Flynn, Sam
Thomas, Russell
Subiel, Anna
Lee, Nigel
Shipley, David
Palmans, Hugo
Lourenço, Ana
Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title_full Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title_fullStr Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title_full_unstemmed Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title_short Monte Carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
title_sort monte carlo modelling of a prototype small-body portable graphite calorimeter for ultra-high dose rate proton beams
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692912/
https://www.ncbi.nlm.nih.gov/pubmed/38045641
http://dx.doi.org/10.1016/j.phro.2023.100506
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