Quantification of cell death and proliferation of patient-derived ovarian cancer organoids through 3D imaging and image analysis

Patient-derived organoids (PDOs) are ideal ex vivo model systems to study cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring drug efficacy in three-dimensional (3D) high-grade serous ovarian cancer PDO cultures through quantification of cytotoxicity using pr...

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Detalles Bibliográficos
Autores principales: Skorda, Aikaterini, Lauridsen, Anna Røssberg, Huhtinen, Kaisa, Lahtinen, Alexandra, Senkowski, Wojciech, Oikkonen, Jaana, Hynninen, Johanna, Hautaniemi, Sampsa, Kallunki, Tuula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692951/
https://www.ncbi.nlm.nih.gov/pubmed/37976153
http://dx.doi.org/10.1016/j.xpro.2023.102683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692951/
https://www.ncbi.nlm.nih.gov/pubmed/37976153
http://dx.doi.org/10.1016/j.xpro.2023.102683

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