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Quantification of cell death and proliferation of patient-derived ovarian cancer organoids through 3D imaging and image analysis
Patient-derived organoids (PDOs) are ideal ex vivo model systems to study cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring drug efficacy in three-dimensional (3D) high-grade serous ovarian cancer PDO cultures through quantification of cytotoxicity using pr...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692951/ https://www.ncbi.nlm.nih.gov/pubmed/37976153 http://dx.doi.org/10.1016/j.xpro.2023.102683 |