An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan

Measles is a highly contagious infection that leads to many serious complications. Despite the significant global effort to eradicate it, it still represents a major threat due to suboptimal vaccination coverage, especially after the coronavirus disease 2019 (COVID-19) pandemic that affected all rou...

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Autores principales: Kanaan, Dana, Al-Khazali, Mohammad N, Khalid, Israa W, Abu-Ekteish, Faisal, Al-Sweedan, Suleimman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692959/
https://www.ncbi.nlm.nih.gov/pubmed/38046741
http://dx.doi.org/10.7759/cureus.48144
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author Kanaan, Dana
Al-Khazali, Mohammad N
Khalid, Israa W
Abu-Ekteish, Faisal
Al-Sweedan, Suleimman
author_facet Kanaan, Dana
Al-Khazali, Mohammad N
Khalid, Israa W
Abu-Ekteish, Faisal
Al-Sweedan, Suleimman
author_sort Kanaan, Dana
collection PubMed
description Measles is a highly contagious infection that leads to many serious complications. Despite the significant global effort to eradicate it, it still represents a major threat due to suboptimal vaccination coverage, especially after the coronavirus disease 2019 (COVID-19) pandemic that affected all routine childhood vaccinations. One of its fatal complications, which has been reported a few times in the literature, is hemophagocytic lymphohistiocytosis (HLH). We discuss a case of a 14-month-old unvaccinated female patient who developed measles-induced HLH and was treated with intravenous immunoglobulins (IVIG) and steroids; unfortunately, she developed multiorgan failure and passed away before chemotherapy could be initiated.
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spelling pubmed-106929592023-12-03 An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan Kanaan, Dana Al-Khazali, Mohammad N Khalid, Israa W Abu-Ekteish, Faisal Al-Sweedan, Suleimman Cureus Pediatrics Measles is a highly contagious infection that leads to many serious complications. Despite the significant global effort to eradicate it, it still represents a major threat due to suboptimal vaccination coverage, especially after the coronavirus disease 2019 (COVID-19) pandemic that affected all routine childhood vaccinations. One of its fatal complications, which has been reported a few times in the literature, is hemophagocytic lymphohistiocytosis (HLH). We discuss a case of a 14-month-old unvaccinated female patient who developed measles-induced HLH and was treated with intravenous immunoglobulins (IVIG) and steroids; unfortunately, she developed multiorgan failure and passed away before chemotherapy could be initiated. Cureus 2023-11-02 /pmc/articles/PMC10692959/ /pubmed/38046741 http://dx.doi.org/10.7759/cureus.48144 Text en Copyright © 2023, Kanaan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Kanaan, Dana
Al-Khazali, Mohammad N
Khalid, Israa W
Abu-Ekteish, Faisal
Al-Sweedan, Suleimman
An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title_full An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title_fullStr An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title_full_unstemmed An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title_short An Unusual Complication of Measles Infection in a Pediatric Patient: A Case Report of Measles-Induced Hemophagocytic Lymphohistiocytosis (HLH) From Jordan
title_sort unusual complication of measles infection in a pediatric patient: a case report of measles-induced hemophagocytic lymphohistiocytosis (hlh) from jordan
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692959/
https://www.ncbi.nlm.nih.gov/pubmed/38046741
http://dx.doi.org/10.7759/cureus.48144
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