Molecular docking analysis of quercetin with known CoVid-19 targets

Combat and care during CoVid-19 was non-trivial. Therefore, it is of interest to use the pharmacologically active plant component quercetin for the treatment of CoVid-19. Quercetin exhibits favourable ADMET values and abides by Lipinski's rule of five. When quercetin and remdesivir were positio...

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Detalles Bibliográficos
Autores principales: Chandran, Sridevi Chandra Subash, Christopher, Ireen, Sounderraajan, Aishwariya, Murugesan, Viji, Sabapathy, Indu, Periyasamy, Vijayalakshmi, Manikkam, Rajalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692980/
https://www.ncbi.nlm.nih.gov/pubmed/38046509
http://dx.doi.org/10.6026/973206300191081
Descripción
Sumario:Combat and care during CoVid-19 was non-trivial. Therefore, it is of interest to use the pharmacologically active plant component quercetin for the treatment of CoVid-19. Quercetin exhibits favourable ADMET values and abides by Lipinski's rule of five. When quercetin and remdesivir were positioned in relation to the CoVid-19 targets, quercetin exhibited a greater propensity for binding and H-bond interaction in their molecular interactions. Thus, the quercetin molecule can be used to manage CoVid-19.

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