Cargando…

Down-regulation of COL1A1 inhibits tumor-associated fibroblast activation and mediates matrix remodeling in the tumor microenvironment of breast cancer

We investigated the effects of collagen type I alpha 1 (COL1A1) on tumor-associated fibroblast activation and matrix remodeling in the tumor microenvironment of breast cancer. Cells were divided into the blank control, negative control, and siRNA-COL1A1 groups, or HKF control, HKF + exosomes (EXO),...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Bin, Li, Fangfang, Ma, Binlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693014/
https://www.ncbi.nlm.nih.gov/pubmed/38045487
http://dx.doi.org/10.1515/biol-2022-0776