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Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells

BACKGROUND: Despite recent advances in locoregional, systemic, and novel checkpoint inhibitor treatment, hepatocellular carcinoma (HCC) is still associated with poor prognosis. The feasibility of potentially curative liver resection (LR) and transplantation (LT) is limited by the underlying liver di...

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Detalles Bibliográficos
Autores principales:	Koch, Dominik T., Yu, Haochen, Beirith, Iris, Schirren, Malte, Drefs, Moritz, Liu, Yunfei, Knoblauch, Mathilda, Koliogiannis, Dionysios, Sheng, Weiwei, De Toni, Enrico N., Bazhin, Alexandr V., Renz, Bernhard W., Guba, Markus O., Werner, Jens, Ilmer, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693093/ https://www.ncbi.nlm.nih.gov/pubmed/38041179 http://dx.doi.org/10.1186/s12967-023-04615-4

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