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Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation

BACKGROUND: Asthma is a heterogenous disease that characterized by airway remodeling. SYVN1 (Synoviolin 1) acts as an E3 ligase to mediate the suppression of endoplasmic reticulum (ER) stress through ubiquitination and degradation. However, the role of SYVN1 in the pathogenesis of asthma is unclear....

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Detalles Bibliográficos
Autores principales:	Dai, Bing, Liu, Si, Shen, Wenxin, Chen, Li, Zhou, Qianlan, Han, Lina, Zhang, Qinzhen, Shan, Lishen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693155/ https://www.ncbi.nlm.nih.gov/pubmed/38041162 http://dx.doi.org/10.1186/s40659-023-00478-7

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