Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants

BACKGROUND: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has challenged the effectiveness of current therapeutic regimens. Here, we aimed to develop a potent SARS-CoV-2 antibody with broad neutralizing effect by screening a scFv library with the spike protei...

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Detalles Bibliográficos
Autores principales: Ko, Hae Li, Lee, Deuk-ki, Kim, Younghyeon, Jang, Hui Jeong, Lee, Youn Woo, Lee, Ho-Young, Seok, Sang-Hyuk, Park, Jun Won, Limb, Jin-Kyung, On, Da In, Yun, Jun-Won, Lyoo, Kwang-Soo, Song, Daesub, Yeom, Minjoo, Lee, Hanbyeul, Seong, Je Kyung, Lee, Sungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693169/
https://www.ncbi.nlm.nih.gov/pubmed/38041113
http://dx.doi.org/10.1186/s12985-023-02230-9

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