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BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells

Mammalian haploid cells are important resources for forward genetic screening and are important in genetic medicine and drug development. However, the self‐diploidization of murine haploid embryonic stem cells (haESCs) during daily culture or differentiation jeopardizes their use in genetic approach...

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Detalles Bibliográficos
Autores principales: Sun, Shengyi, Zhao, Qin, Zhao, Yiding, Geng, Mengyang, Wang, Qing, Gao, Qian, Zhang, Xiao‐Ou, Zhang, Wenhao, Shuai, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693186/
https://www.ncbi.nlm.nih.gov/pubmed/37144356
http://dx.doi.org/10.1111/cpr.13498