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Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan

OBJECTIVE: A multitude of previous studies has substantiated that endometriosis correlated highly with psychiatric health. This study aims to investigate the association between endometriosis and psychiatric health. METHODS: Utilizing the National Health Insurance Research Database of Taiwan, 100,77...

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Autores principales: Wang, Tsan-Min, Lee, Yi-Liang, Chung, Chi-Hsiang, Sun, Chien-An, Kang, Chieh-Yi, Wu, Gwo-Jang, Chien, Wu-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693200/
https://www.ncbi.nlm.nih.gov/pubmed/38046265
http://dx.doi.org/10.2147/IJWH.S430252
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author Wang, Tsan-Min
Lee, Yi-Liang
Chung, Chi-Hsiang
Sun, Chien-An
Kang, Chieh-Yi
Wu, Gwo-Jang
Chien, Wu-Chien
author_facet Wang, Tsan-Min
Lee, Yi-Liang
Chung, Chi-Hsiang
Sun, Chien-An
Kang, Chieh-Yi
Wu, Gwo-Jang
Chien, Wu-Chien
author_sort Wang, Tsan-Min
collection PubMed
description OBJECTIVE: A multitude of previous studies has substantiated that endometriosis correlated highly with psychiatric health. This study aims to investigate the association between endometriosis and psychiatric health. METHODS: Utilizing the National Health Insurance Research Database of Taiwan, 100,770 enrolled participants, including 20,154 patients with endometriosis and 80,616 in the control group (1:4), matched for age, and index date from Taiwan’s Longitudinal Health Insurance Database between January 1, 2000, and December 31, 2015. The Cox proportional regression model was used to compare the risk of mental disorders during the 16 years of follow-up after adjusting for confounding factors. RESULTS: Of the study patients, 4083 (20.26%) developed mental disorders; 9225 of the 80,616 controls (11.44%) developed mental disorders. The Cox regression demonstrated that, after adjusting for age, monthly income, urbanization level, etc., people with endometriosis are more likely to suffer from mental disorders compared to those without endometriosis (hazard ratio [HR]=2.131; 95% confidence interval [CI]= 1.531–2.788; p<0.001). The result illustrated that women over 40 years old had a more significant risk. CONCLUSION: Compared to people without endometriosis, this study provides evidence that patients with endometriosis are at a 2.131-fold higher risk of developing mental disorders, especially in elder women. Regular psychiatric follow-up might be needed for those patients.
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spelling pubmed-106932002023-12-03 Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan Wang, Tsan-Min Lee, Yi-Liang Chung, Chi-Hsiang Sun, Chien-An Kang, Chieh-Yi Wu, Gwo-Jang Chien, Wu-Chien Int J Womens Health Original Research OBJECTIVE: A multitude of previous studies has substantiated that endometriosis correlated highly with psychiatric health. This study aims to investigate the association between endometriosis and psychiatric health. METHODS: Utilizing the National Health Insurance Research Database of Taiwan, 100,770 enrolled participants, including 20,154 patients with endometriosis and 80,616 in the control group (1:4), matched for age, and index date from Taiwan’s Longitudinal Health Insurance Database between January 1, 2000, and December 31, 2015. The Cox proportional regression model was used to compare the risk of mental disorders during the 16 years of follow-up after adjusting for confounding factors. RESULTS: Of the study patients, 4083 (20.26%) developed mental disorders; 9225 of the 80,616 controls (11.44%) developed mental disorders. The Cox regression demonstrated that, after adjusting for age, monthly income, urbanization level, etc., people with endometriosis are more likely to suffer from mental disorders compared to those without endometriosis (hazard ratio [HR]=2.131; 95% confidence interval [CI]= 1.531–2.788; p<0.001). The result illustrated that women over 40 years old had a more significant risk. CONCLUSION: Compared to people without endometriosis, this study provides evidence that patients with endometriosis are at a 2.131-fold higher risk of developing mental disorders, especially in elder women. Regular psychiatric follow-up might be needed for those patients. Dove 2023-11-28 /pmc/articles/PMC10693200/ /pubmed/38046265 http://dx.doi.org/10.2147/IJWH.S430252 Text en © 2023 Wang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Wang, Tsan-Min
Lee, Yi-Liang
Chung, Chi-Hsiang
Sun, Chien-An
Kang, Chieh-Yi
Wu, Gwo-Jang
Chien, Wu-Chien
Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title_full Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title_fullStr Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title_full_unstemmed Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title_short Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan
title_sort association between endometriosis and mental disorders including psychiatric disorders, suicide, and all-cause mortality -a nationwide population-based cohort study in taiwan
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693200/
https://www.ncbi.nlm.nih.gov/pubmed/38046265
http://dx.doi.org/10.2147/IJWH.S430252
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