Cargando…

The Characteristics of Transcription Factors Regulating T Cell Exhaustion Were Analyzed to Predict the Prognosis and Therapeutic Effect in Patients with HCC

PURPOSE: Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related deaths, posing a significant threat to people in diverse regions. T-cell exhaustion (Tex) can hinder the efficacy of immunotherapy in patients with HCC, and the transcription factors that regulate Tex in HCC h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jingbo, Zhou, Kun, Wu, Meng, Zhang, Rongzheng, Jin, Xi, Qiao, Han, Li, Jiaqi, Cao, Xinyang, Zhang, Shuyun, Dong, Guanglu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693252/ https://www.ncbi.nlm.nih.gov/pubmed/38045905 http://dx.doi.org/10.2147/IJGM.S435620

Ejemplares similares

The necroptosis related gene LGALS3 can be used as a biomarker for the adverse progression from chronic HBV infection to HCC
por: Dong, Jianming, et al.
Publicado: (2023)

Comprehensive Analysis of m7G-Related Genes and Chronic Hepatitis B: Diagnostic Markers, Immune Microenvironment Regulation, Disease Progression
por: Zhang, Rongzheng, et al.
Publicado: (2023)

Development and validation of a necroptosis-related gene prognostic score to predict prognosis and efficiency of immunotherapy in gastric cancer
por: Xia, Yan, et al.
Publicado: (2022)

Establishment and validation of exhausted CD8+ T cell feature as a prognostic model of HCC
por: Shi, Jihang, et al.
Publicado: (2023)

Mutational and transcriptional alterations and clinicopathological factors predict the prognosis of stage I hepatocellular carcinoma: Prediction of stage I HCC prognosis
por: Li, Zhiqiang, et al.
Publicado: (2022)

The Association of HMGB1 Gene with the Prognosis of HCC
por: Xiao, Jianbiao, et al.
Publicado: (2014)

T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
por: Chi, Hao, et al.
Publicado: (2023)

TSC2 Mutations Were Associated with the Early Recurrence of Patients with HCC Underwent Hepatectomy
por: Song, Kangjian, et al.
Publicado: (2021)

GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression
por: Zhang, Zhuoliang, et al.
Publicado: (2021)

GATA3 is downregulated in HCC and accelerates HCC aggressiveness by transcriptionally inhibiting slug expression
por: Zhang, Zhuoliang, et al.
Publicado: (2021)

Elevated Serum Uric Acid is Associated With Poor Survival in Advanced HCC Patients and Febuxostat Improves Prognosis in HCC Rats
por: Wu, Le, et al.
Publicado: (2021)

Olfm4 Is Highly Expressed in HCC Patients and as a Biomarker and Therapeutic Target for HCC
por: Wei, Yulong, et al.
Publicado: (2021)

Identification of Prognosis-Related Oxidative Stress Model with Immunosuppression in HCC
por: Ren, Zhixuan, et al.
Publicado: (2023)

Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion
por: Hu, Xichen, et al.
Publicado: (2023)

Screening the genome for HCC-specific CpG methylation signatures as biomarkers for diagnosis and prognosis evaluation
por: Zhang, Rui-kun, et al.
Publicado: (2021)

Integrating machine learning and single-cell trajectories to analyze T-cell exhaustion to predict prognosis and immunotherapy in colon cancer patients
por: Shen, Xiaogang, et al.
Publicado: (2023)

KIF14 and KIF23 Promote Cell Proliferation and Chemoresistance in HCC Cells, and Predict Worse Prognosis of Patients with HCC
por: Cheng, Chunxia, et al.
Publicado: (2020)

Preoperative inflammatory markers of NLR and PLR as indicators of poor prognosis in resectable HCC
por: Wang, Dong, et al.
Publicado: (2019)

Therapeutic Strategies in HCC: Radiation Modalities
por: Gallicchio, R., et al.
Publicado: (2016)

ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC
por: Wang, Huihui, et al.
Publicado: (2023)

DHX37 Is a Promising Prognostic Biomarker and a Therapeutic Target for Immunotherapy and Chemotherapy in HCC
por: Liu, Nanbin, et al.
Publicado: (2023)

A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC
por: Rao, Zuqin, et al.
Publicado: (2022)

The Association between Artificial Intelligence Awareness and Employee Depression: The Mediating Role of Emotional Exhaustion and the Moderating Role of Perceived Organizational Support
por: Xu, Guanglu, et al.
Publicado: (2023)

Using cell-free DNA for HCC surveillance and prognosis
por: Tran, Nguyen H., et al.
Publicado: (2021)

Retraction: The Association of HMGB1 Gene with the Prognosis of HCC
Publicado: (2023)

The Mechanism of Rac1 in Regulating HCC Cell Glycolysis Which Provides Underlying Therapeutic Target for HCC Therapy
por: Ren, Yin-Xiang, et al.
Publicado: (2022)

Cuproptosis-related prognostic signatures predict the prognosis and immunotherapy in HCC patients
por: Peng, Hong, et al.
Publicado: (2023)

Investigating the Promoter of FAT10 Gene in HCC Patients
por: Liu, Shuaichen, et al.
Publicado: (2018)

T Cell Dysfunction and Exhaustion in Cancer
por: Zhang, Zhen, et al.
Publicado: (2020)

Circular RNA as a Novel Biomarker and Therapeutic Target for HCC
por: Meng, Hongwu, et al.
Publicado: (2022)

Prognostic Nutritional Index and Systemic Immune-Inflammation Index Predict the Prognosis of Patients with HCC
por: Wang, Dong, et al.
Publicado: (2020)

B cell subsets were associated with prognosis in elderly patients with community acquired pneumonia
por: Wang, Chun-Mei, et al.
Publicado: (2022)

Tumor PHD2 Expression Is Correlated With Clinical Features and Prognosis of Patients With HCC Receiving Liver Resection
por: Zhen, Li, et al.
Publicado: (2014)

Eleven metabolism‑related genes composed of Stard5 predict prognosis and contribute to EMT phenotype in HCC
por: Li, Dongping, et al.
Publicado: (2023)

The Function and Prognostic Value of RNA-Binding Proteins in Colorectal Adenocarcinoma Were Analyzed Based on Bioinformatics of Smart Medical Big Data
por: Zhao, Haoran, et al.
Publicado: (2021)

Why we need to report more than 'Data were Analyzed by t-tests or ANOVA'
por: Weissgerber, Tracey L, et al.
Publicado: (2018)

Decreased Expression of ZWINT is Associated With Poor Prognosis in Patients With HCC After Surgery
por: Yang, Xiao-Yu, et al.
Publicado: (2018)

Efficacy of adjuvant TACE on the prognosis of patients with HCC after hepatectomy: a multicenter propensity score matching from China
por: Wu, Zhao, et al.
Publicado: (2023)

Cancer Progression Mediated by CAFs Relating to HCC and Identification of Genetic Characteristics Influencing Prognosis
por: Song, Li, et al.
Publicado: (2022)

Exhausted Capacity of Bicarbonate Buffer in Renal Failure Diagnosed Using Point of Care Analyzer
por: Gołębiowski, Tomasz, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6dhntug66mi680uq6sbise78tg