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Automatic segmentation of mandibular canal using transformer based neural networks

Accurate 3D localization of the mandibular canal is crucial for the success of digitally-assisted dental surgeries. Damage to the mandibular canal may result in severe consequences for the patient, including acute pain, numbness, or even facial paralysis. As such, the development of a fast, stable,...

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Autores principales: Lv, Jinxuan, Zhang, Lang, Xu, Jiajie, Li, Wang, Li, Gen, Zhou, Hengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693337/
https://www.ncbi.nlm.nih.gov/pubmed/38047288
http://dx.doi.org/10.3389/fbioe.2023.1302524
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author Lv, Jinxuan
Zhang, Lang
Xu, Jiajie
Li, Wang
Li, Gen
Zhou, Hengyu
author_facet Lv, Jinxuan
Zhang, Lang
Xu, Jiajie
Li, Wang
Li, Gen
Zhou, Hengyu
author_sort Lv, Jinxuan
collection PubMed
description Accurate 3D localization of the mandibular canal is crucial for the success of digitally-assisted dental surgeries. Damage to the mandibular canal may result in severe consequences for the patient, including acute pain, numbness, or even facial paralysis. As such, the development of a fast, stable, and highly precise method for mandibular canal segmentation is paramount for enhancing the success rate of dental surgical procedures. Nonetheless, the task of mandibular canal segmentation is fraught with challenges, including a severe imbalance between positive and negative samples and indistinct boundaries, which often compromise the completeness of existing segmentation methods. To surmount these challenges, we propose an innovative, fully automated segmentation approach for the mandibular canal. Our methodology employs a Transformer architecture in conjunction with cl-Dice loss to ensure that the model concentrates on the connectivity of the mandibular canal. Additionally, we introduce a pixel-level feature fusion technique to bolster the model’s sensitivity to fine-grained details of the canal structure. To tackle the issue of sample imbalance and vague boundaries, we implement a strategy founded on mandibular foramen localization to isolate the maximally connected domain of the mandibular canal. Furthermore, a contrast enhancement technique is employed for pre-processing the raw data. We also adopt a Deep Label Fusion strategy for pre-training on synthetic datasets, which substantially elevates the model’s performance. Empirical evaluations on a publicly accessible mandibular canal dataset reveal superior performance metrics: a Dice score of 0.844, click score of 0.961, IoU of 0.731, and HD95 of 2.947 mm. These results not only validate the efficacy of our approach but also establish its state-of-the-art performance on the public mandibular canal dataset.
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spelling pubmed-106933372023-12-03 Automatic segmentation of mandibular canal using transformer based neural networks Lv, Jinxuan Zhang, Lang Xu, Jiajie Li, Wang Li, Gen Zhou, Hengyu Front Bioeng Biotechnol Bioengineering and Biotechnology Accurate 3D localization of the mandibular canal is crucial for the success of digitally-assisted dental surgeries. Damage to the mandibular canal may result in severe consequences for the patient, including acute pain, numbness, or even facial paralysis. As such, the development of a fast, stable, and highly precise method for mandibular canal segmentation is paramount for enhancing the success rate of dental surgical procedures. Nonetheless, the task of mandibular canal segmentation is fraught with challenges, including a severe imbalance between positive and negative samples and indistinct boundaries, which often compromise the completeness of existing segmentation methods. To surmount these challenges, we propose an innovative, fully automated segmentation approach for the mandibular canal. Our methodology employs a Transformer architecture in conjunction with cl-Dice loss to ensure that the model concentrates on the connectivity of the mandibular canal. Additionally, we introduce a pixel-level feature fusion technique to bolster the model’s sensitivity to fine-grained details of the canal structure. To tackle the issue of sample imbalance and vague boundaries, we implement a strategy founded on mandibular foramen localization to isolate the maximally connected domain of the mandibular canal. Furthermore, a contrast enhancement technique is employed for pre-processing the raw data. We also adopt a Deep Label Fusion strategy for pre-training on synthetic datasets, which substantially elevates the model’s performance. Empirical evaluations on a publicly accessible mandibular canal dataset reveal superior performance metrics: a Dice score of 0.844, click score of 0.961, IoU of 0.731, and HD95 of 2.947 mm. These results not only validate the efficacy of our approach but also establish its state-of-the-art performance on the public mandibular canal dataset. Frontiers Media S.A. 2023-11-17 /pmc/articles/PMC10693337/ /pubmed/38047288 http://dx.doi.org/10.3389/fbioe.2023.1302524 Text en Copyright © 2023 Lv, Zhang, Xu, Li, Li and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Lv, Jinxuan
Zhang, Lang
Xu, Jiajie
Li, Wang
Li, Gen
Zhou, Hengyu
Automatic segmentation of mandibular canal using transformer based neural networks
title Automatic segmentation of mandibular canal using transformer based neural networks
title_full Automatic segmentation of mandibular canal using transformer based neural networks
title_fullStr Automatic segmentation of mandibular canal using transformer based neural networks
title_full_unstemmed Automatic segmentation of mandibular canal using transformer based neural networks
title_short Automatic segmentation of mandibular canal using transformer based neural networks
title_sort automatic segmentation of mandibular canal using transformer based neural networks
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693337/
https://www.ncbi.nlm.nih.gov/pubmed/38047288
http://dx.doi.org/10.3389/fbioe.2023.1302524
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