P2rx1 deficiency alleviates acetaminophen-induced acute liver failure by regulating the STING signaling pathway

AIMS: Purinergic signaling-mediated mitochondria dysfunction and innate immune-mediated inflammation act as triggers during acetaminophen (APAP)-induced liver injury (AILI). However, the underlying mechanisms by which purinoceptor regulates mitochondria function and inflammation response in the prog...

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Detalles Bibliográficos
Autores principales: Yu, Yeping, Chang, Ling, Hu, Qingluan, Zhu, Jianjun, Zhang, Jianjun, Xia, Qiang, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693536/
https://www.ncbi.nlm.nih.gov/pubmed/37046119
http://dx.doi.org/10.1007/s10565-023-09800-1

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