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Identification of intergenerational epigenetic inheritance by whole genome DNA methylation analysis in trios

Genome-wide association studies have identified thousands of loci associated with common diseases and traits. However, a large fraction of heritability remains unexplained. Epigenetic modifications, such as the observed in DNA methylation have been proposed as a mechanism of intergenerational inheri...

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Detalles Bibliográficos
Autores principales: Díez-Villanueva, Anna, Martín, Berta, Moratalla-Navarro, Ferran, Morón-Duran, Francisco D., Galván-Femenía, Iván, Obón-Santacana, Mireia, Carreras, Anna, de Cid, Rafael, Peinado, Miguel A., Moreno, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693549/
https://www.ncbi.nlm.nih.gov/pubmed/38042866
http://dx.doi.org/10.1038/s41598-023-48517-3