Cargando…
Identification of intergenerational epigenetic inheritance by whole genome DNA methylation analysis in trios
Genome-wide association studies have identified thousands of loci associated with common diseases and traits. However, a large fraction of heritability remains unexplained. Epigenetic modifications, such as the observed in DNA methylation have been proposed as a mechanism of intergenerational inheri...
Autores principales: | Díez-Villanueva, Anna, Martín, Berta, Moratalla-Navarro, Ferran, Morón-Duran, Francisco D., Galván-Femenía, Iván, Obón-Santacana, Mireia, Carreras, Anna, de Cid, Rafael, Peinado, Miguel A., Moreno, Victor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693549/ https://www.ncbi.nlm.nih.gov/pubmed/38042866 http://dx.doi.org/10.1038/s41598-023-48517-3 |
Ejemplares similares
-
GCAT|Genomes for life: a prospective cohort study of the genomes of Catalonia
por: Obón-Santacana, Mireia, et al.
Publicado: (2018) -
Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci
por: Díez-Obrero, Virginia, et al.
Publicado: (2021) -
Intergenerational epigenetic inheritance of cancer susceptibility in mammals
por: Lesch, Bluma J, et al.
Publicado: (2019) -
Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort
por: Galván-Femenía, Iván, et al.
Publicado: (2018) -
Utf1 contributes to intergenerational epigenetic inheritance of pluripotency
por: Bao, Qiuye, et al.
Publicado: (2017)