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Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis

This cross-sectional study presents the nutritional status of newly diagnosed pediatric patients with Crohn’s disease (CD) and ulcerative colitis (UC) and its association with the duration of the disease and selected clinical features. We analyzed the data of 41 pediatric patients with CD and 29 wit...

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Autores principales: Pawłowska-Seredyńska, Katarzyna, Akutko, Katarzyna, Umławska, Wioleta, Śmieszniak, Bartłomiej, Seredyński, Rafał, Stawarski, Andrzej, Pytrus, Tomasz, Iwańczak, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693555/
https://www.ncbi.nlm.nih.gov/pubmed/38042899
http://dx.doi.org/10.1038/s41598-023-48504-8
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author Pawłowska-Seredyńska, Katarzyna
Akutko, Katarzyna
Umławska, Wioleta
Śmieszniak, Bartłomiej
Seredyński, Rafał
Stawarski, Andrzej
Pytrus, Tomasz
Iwańczak, Barbara
author_facet Pawłowska-Seredyńska, Katarzyna
Akutko, Katarzyna
Umławska, Wioleta
Śmieszniak, Bartłomiej
Seredyński, Rafał
Stawarski, Andrzej
Pytrus, Tomasz
Iwańczak, Barbara
author_sort Pawłowska-Seredyńska, Katarzyna
collection PubMed
description This cross-sectional study presents the nutritional status of newly diagnosed pediatric patients with Crohn’s disease (CD) and ulcerative colitis (UC) and its association with the duration of the disease and selected clinical features. We analyzed the data of 41 pediatric patients with CD and 29 with UC (mean age: 13.1 y, range: 5.2–18.0 y) up to 3 mo. from diagnosis. Anthropometry included body weight, body height, body mass index (BMI), three skinfold thicknesses, mid-upper arm circumference and mid-upper arm muscle circumference adjusted for age and sex using national standards. Anthropometry was linked to the disease duration, location of the disease, symptoms, and blood test results. Both studied groups presented significantly lower BMI compared to the reference population, but only children with CD characterized with significantly worse nutritional status according to arm anthropometry. In CD, better nutritional status was associated mainly with longer disease duration and, to a lesser extent, with extraintestinal manifestations, perianal disease, and small intestinal lesions. In UC, anemia at diagnosis was associated with poor nutritional status. Our finding emphasizes the need for more attentive diagnostic care for pediatric patients who exhibit extraintestinal symptoms or perianal disease with no obvious signs of malnutrition, to avoid diagnostic delays.
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spelling pubmed-106935552023-12-04 Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis Pawłowska-Seredyńska, Katarzyna Akutko, Katarzyna Umławska, Wioleta Śmieszniak, Bartłomiej Seredyński, Rafał Stawarski, Andrzej Pytrus, Tomasz Iwańczak, Barbara Sci Rep Article This cross-sectional study presents the nutritional status of newly diagnosed pediatric patients with Crohn’s disease (CD) and ulcerative colitis (UC) and its association with the duration of the disease and selected clinical features. We analyzed the data of 41 pediatric patients with CD and 29 with UC (mean age: 13.1 y, range: 5.2–18.0 y) up to 3 mo. from diagnosis. Anthropometry included body weight, body height, body mass index (BMI), three skinfold thicknesses, mid-upper arm circumference and mid-upper arm muscle circumference adjusted for age and sex using national standards. Anthropometry was linked to the disease duration, location of the disease, symptoms, and blood test results. Both studied groups presented significantly lower BMI compared to the reference population, but only children with CD characterized with significantly worse nutritional status according to arm anthropometry. In CD, better nutritional status was associated mainly with longer disease duration and, to a lesser extent, with extraintestinal manifestations, perianal disease, and small intestinal lesions. In UC, anemia at diagnosis was associated with poor nutritional status. Our finding emphasizes the need for more attentive diagnostic care for pediatric patients who exhibit extraintestinal symptoms or perianal disease with no obvious signs of malnutrition, to avoid diagnostic delays. Nature Publishing Group UK 2023-12-02 /pmc/articles/PMC10693555/ /pubmed/38042899 http://dx.doi.org/10.1038/s41598-023-48504-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pawłowska-Seredyńska, Katarzyna
Akutko, Katarzyna
Umławska, Wioleta
Śmieszniak, Bartłomiej
Seredyński, Rafał
Stawarski, Andrzej
Pytrus, Tomasz
Iwańczak, Barbara
Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title_full Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title_fullStr Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title_full_unstemmed Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title_short Nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
title_sort nutritional status of pediatric patients with inflammatory bowel diseases is related to disease duration and clinical picture at diagnosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693555/
https://www.ncbi.nlm.nih.gov/pubmed/38042899
http://dx.doi.org/10.1038/s41598-023-48504-8
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