Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling

Paneth cell metaplasia (PCM) typically arises in pre-existing gastrointestinal (GI) diseases; however, the mechanistic pathway that induces metaplasia and whether PCM is initiated exclusively by disorders intrinsic to the GI tract is not well known. Here, we describe the development of PCM in a muri...

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Detalles Bibliográficos
Autores principales: Yuan, Chengyin, Rayasam, Aditya, Moe, Alison, Hayward, Michael, Wells, Clive, Szabo, Aniko, Mackenzie, Andrew, Salzman, Nita, Drobyski, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693577/
https://www.ncbi.nlm.nih.gov/pubmed/38042840
http://dx.doi.org/10.1038/s41467-023-43248-5

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