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Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states

Herpesviruses remain a burden for animal and human health, including the medically important varicella-zoster virus (VZV). Membrane fusion mediated by conserved core glycoproteins, the fusogen gB and the heterodimer gH-gL, enables herpesvirus cell entry. The ectodomain of gB orthologs has five domai...

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Detalles Bibliográficos
Autores principales:	Zhou, Momei, Vollmer, Benjamin, Machala, Emily, Chen, Muyuan, Grünewald, Kay, Arvin, Ann M., Chiu, Wah, Oliver, Stefan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693595/ https://www.ncbi.nlm.nih.gov/pubmed/38042814 http://dx.doi.org/10.1038/s41467-023-43011-w

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