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Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations

Infants necessitate vaccinations to prevent life-threatening infections. Our understanding of the infant immune responses to routine vaccines remains limited. We analyzed two cohorts of 2-month-old infants before vaccination, one week, and one-month post-vaccination. We report remarkable heterogenei...

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Detalles Bibliográficos
Autores principales: Nouri, Nima, Cao, Raquel Giacomelli, Bunsow, Eleonora, Nehar-Belaid, Djamel, Marches, Radu, Xu, Zhaohui, Smith, Bennett, Heinonen, Santtu, Mertz, Sara, Leber, Amy, Smits, Gaby, van der Klis, Fiona, Mejías, Asunción, Banchereau, Jacques, Pascual, Virginia, Ramilo, Octavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693608/
https://www.ncbi.nlm.nih.gov/pubmed/38042900
http://dx.doi.org/10.1038/s41467-023-43758-2