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Oral micro-electronic platform for temperature and humidity monitoring

Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature...

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Autores principales: Popović, Željko V., Thiha, Aung, Ibrahim, Fatimah, Petrović, Bojan B., Dahlan, Nuraina Anisa, Milić, Lazar, Kojić, Sanja, Stojanović, Goran M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693621/
https://www.ncbi.nlm.nih.gov/pubmed/38042878
http://dx.doi.org/10.1038/s41598-023-48379-9
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author Popović, Željko V.
Thiha, Aung
Ibrahim, Fatimah
Petrović, Bojan B.
Dahlan, Nuraina Anisa
Milić, Lazar
Kojić, Sanja
Stojanović, Goran M.
author_facet Popović, Željko V.
Thiha, Aung
Ibrahim, Fatimah
Petrović, Bojan B.
Dahlan, Nuraina Anisa
Milić, Lazar
Kojić, Sanja
Stojanović, Goran M.
author_sort Popović, Željko V.
collection PubMed
description Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike.
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spelling pubmed-106936212023-12-04 Oral micro-electronic platform for temperature and humidity monitoring Popović, Željko V. Thiha, Aung Ibrahim, Fatimah Petrović, Bojan B. Dahlan, Nuraina Anisa Milić, Lazar Kojić, Sanja Stojanović, Goran M. Sci Rep Article Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike. Nature Publishing Group UK 2023-12-02 /pmc/articles/PMC10693621/ /pubmed/38042878 http://dx.doi.org/10.1038/s41598-023-48379-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Popović, Željko V.
Thiha, Aung
Ibrahim, Fatimah
Petrović, Bojan B.
Dahlan, Nuraina Anisa
Milić, Lazar
Kojić, Sanja
Stojanović, Goran M.
Oral micro-electronic platform for temperature and humidity monitoring
title Oral micro-electronic platform for temperature and humidity monitoring
title_full Oral micro-electronic platform for temperature and humidity monitoring
title_fullStr Oral micro-electronic platform for temperature and humidity monitoring
title_full_unstemmed Oral micro-electronic platform for temperature and humidity monitoring
title_short Oral micro-electronic platform for temperature and humidity monitoring
title_sort oral micro-electronic platform for temperature and humidity monitoring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693621/
https://www.ncbi.nlm.nih.gov/pubmed/38042878
http://dx.doi.org/10.1038/s41598-023-48379-9
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