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Oral micro-electronic platform for temperature and humidity monitoring
Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693621/ https://www.ncbi.nlm.nih.gov/pubmed/38042878 http://dx.doi.org/10.1038/s41598-023-48379-9 |
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author | Popović, Željko V. Thiha, Aung Ibrahim, Fatimah Petrović, Bojan B. Dahlan, Nuraina Anisa Milić, Lazar Kojić, Sanja Stojanović, Goran M. |
author_facet | Popović, Željko V. Thiha, Aung Ibrahim, Fatimah Petrović, Bojan B. Dahlan, Nuraina Anisa Milić, Lazar Kojić, Sanja Stojanović, Goran M. |
author_sort | Popović, Željko V. |
collection | PubMed |
description | Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike. |
format | Online Article Text |
id | pubmed-10693621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-106936212023-12-04 Oral micro-electronic platform for temperature and humidity monitoring Popović, Željko V. Thiha, Aung Ibrahim, Fatimah Petrović, Bojan B. Dahlan, Nuraina Anisa Milić, Lazar Kojić, Sanja Stojanović, Goran M. Sci Rep Article Intraoral theranostics, the integration of diagnostics and therapeutics within the oral cavity, is gaining significant traction. This pioneering approach primarily addresses issues like xerostomia (dry mouth), commonly resulting from cancer treatment, with a specific focus on monitoring temperature and humidity. This paper introduces the innovative Intra-Oral Portable Micro-Electronic (IOPM) fluidic theranostic device platform. It leverages conventional dental spoons by incorporating advanced sensors for precise measurements of oral temperature and humidity. Personalization options include a microfluidic chip and a tooth model, enabling targeted delivery of therapeutic agents to optimize treatment outcomes. The electronic control system simplifies the administration of fluid dosages, intelligently adjusted based on real-time oral cavity temperature and humidity readings. Rigorous experimental evaluations validate the platform’s precision in delivering fluid volumes at predefined intervals. This platform represents a transformative advancement for individuals contending with oral health challenges such as xerostomia (dry mouth). Furthermore, it has the potential to elevate oral healthcare standards by providing advanced diagnostics and tailored therapeutic solutions, benefiting both patients and dental professionals alike. Nature Publishing Group UK 2023-12-02 /pmc/articles/PMC10693621/ /pubmed/38042878 http://dx.doi.org/10.1038/s41598-023-48379-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Popović, Željko V. Thiha, Aung Ibrahim, Fatimah Petrović, Bojan B. Dahlan, Nuraina Anisa Milić, Lazar Kojić, Sanja Stojanović, Goran M. Oral micro-electronic platform for temperature and humidity monitoring |
title | Oral micro-electronic platform for temperature and humidity monitoring |
title_full | Oral micro-electronic platform for temperature and humidity monitoring |
title_fullStr | Oral micro-electronic platform for temperature and humidity monitoring |
title_full_unstemmed | Oral micro-electronic platform for temperature and humidity monitoring |
title_short | Oral micro-electronic platform for temperature and humidity monitoring |
title_sort | oral micro-electronic platform for temperature and humidity monitoring |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693621/ https://www.ncbi.nlm.nih.gov/pubmed/38042878 http://dx.doi.org/10.1038/s41598-023-48379-9 |
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