Extreme deviations from the normative model reveal cortical heterogeneity and associations with negative symptom severity in first-episode psychosis from the OPTiMiSE and GAP studies

There is currently no quantifiable method to predict long-term clinical outcomes in patients presenting with a first episode of psychosis. A major barrier to developing useful markers for this is biological heterogeneity, where many different pathological mechanisms may underly the same set of sympt...

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Detalles Bibliográficos
Autores principales: Worker, Amanda, Berthert, Pierre, Lawrence, Andrew J., Kia, Seyed Mostafa, Arango, Celso, Dinga, Richard, Galderisi, Silvana, Glenthøj, Birte, Kahn, René S., Leslie, Anoushka, Murray, Robin M., Pariante, Carmine M., Pantelis, Christos, Weiser, Mark, Winter-van Rossum, Inge, McGuire, Philip, Dazzan, Paola, Marquand, Andre F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693627/
https://www.ncbi.nlm.nih.gov/pubmed/38042835
http://dx.doi.org/10.1038/s41398-023-02661-6

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