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Accurate de novo peptide sequencing using fully convolutional neural networks

De novo peptide sequencing, which does not rely on a comprehensive target sequence database, provides us with a way to identify novel peptides from tandem mass spectra. However, current de novo sequencing algorithms suffer from low accuracy and coverage, which hinders their application in proteomics...

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Detalles Bibliográficos
Autores principales: Liu, Kaiyuan, Ye, Yuzhen, Li, Sujun, Tang, Haixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693636/
https://www.ncbi.nlm.nih.gov/pubmed/38042873
http://dx.doi.org/10.1038/s41467-023-43010-x

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