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Diversification of division mechanisms in endospore-forming bacteria revealed by analyses of peptidoglycan synthesis in Clostridioides difficile

The bacterial enzymes FtsW and FtsI, encoded in the highly conserved dcw gene cluster, are considered to be universally essential for the synthesis of septal peptidoglycan (PG) during cell division. Here, we show that the pathogen Clostridioides difficile lacks a canonical FtsW/FtsI pair, and its dc...

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Detalles Bibliográficos
Autores principales: Shrestha, Shailab, Taib, Najwa, Gribaldo, Simonetta, Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693644/
https://www.ncbi.nlm.nih.gov/pubmed/38042849
http://dx.doi.org/10.1038/s41467-023-43595-3