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Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions

BACKGROUND: CD1d is a monomorphic major histocompatibility complex class I-like molecule that presents lipid antigens to distinct T-cell subsets and can be expressed by various malignancies. Antibody-mediated targeting of CD1d on multiple myeloma cells was reported to induce apoptosis and could ther...

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Detalles Bibliográficos
Autores principales:	Lameris, Roeland, Shahine, Adam, Veth, Myrthe, Westerman, Bart, Godfrey, Dale I, Lutje Hulsik, David, Brouwer, Patricia, Rossjohn, Jamie, de Gruijl, Tanja D, van der Vliet, Hans J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693867/ https://www.ncbi.nlm.nih.gov/pubmed/38040419 http://dx.doi.org/10.1136/jitc-2023-007631

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