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Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association

OBJECTIVE: In rheumatoid arthritis (RA) around two-thirds of patients are autoantibody positive for rheumatoid factor, anti-citrullinated protein antibodies and/or anti-carbamylated protein antibodies. The remaining seronegative subgroup of patients is clinically heterogeneous and thus far, biomarke...

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Detalles Bibliográficos
Autores principales:	van den Beukel, Michelle D, van Wesemael, Tineke J, Hoogslag, Anna Titia W, Borggreven, Nicole V, Huizinga, Tom WJ, van der Helm-van Mil, Annette HM, Toes, René EM, van der Woude, Diane, Trouw, Leendert A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693877/ http://dx.doi.org/10.1136/rmdopen-2023-003480

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