Cargando…
Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand
This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) to improve disease prevention. The participants were divided into the following 3 groups based on their health status: healthy control (nonOV and nonCCA), those with O. viverrini in...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Parasitology and Tropical Medicine
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693972/ https://www.ncbi.nlm.nih.gov/pubmed/38043542 http://dx.doi.org/10.3347/PHD.23032 |
_version_ | 1785153274606780416 |
---|---|
author | Prasopdee, Sattrachai Rojthongpond, Thittinan Chitkoolsamphan, Yanwadee Pholhelm, Montinee Yusuk, Siraphatsorn Pattaraarchachai, Junya Butthongkomvong, Kritiya Kulsantiwong, Jutharat Phanaksri, Teva Kunjantarachot, Anthicha Tesana, Smarn Sathavornmanee, Thanakrit Thitapakorn, Veerachai |
author_facet | Prasopdee, Sattrachai Rojthongpond, Thittinan Chitkoolsamphan, Yanwadee Pholhelm, Montinee Yusuk, Siraphatsorn Pattaraarchachai, Junya Butthongkomvong, Kritiya Kulsantiwong, Jutharat Phanaksri, Teva Kunjantarachot, Anthicha Tesana, Smarn Sathavornmanee, Thanakrit Thitapakorn, Veerachai |
author_sort | Prasopdee, Sattrachai |
collection | PubMed |
description | This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) to improve disease prevention. The participants were divided into the following 3 groups based on their health status: healthy control (nonOV and nonCCA), those with O. viverrini infection (OV), and those with CCA. A questionnaire was used to explore their lifestyle and behaviors. Multivariate logistic regression and backward elimination were used to identify the significant risk factors. The results showed that the significant risk factors for both O. viverrini infection and CCA were age>50 years (odd ratio (OR)=8.44, P<0.001, 95% confidence intervals (CI) 2.98–23.90 and OR=43.47, P=0.001, 95% CI 14.71–128.45, respectively) and raw fish consumption (OR=8.48, P< 0.001, 95% CI 3.18–22.63 and OR=3.15, P=0.048, 95% CI 1.01–9.86, respectively). A history of O. viverrini infection was identified as an additional risk factor for CCA (OR=20.93, P=0.011, 95% CI 2.04–215.10). This study provided an update on the risk factors for O. viverrini infection and CCA. Asymptomatic patients with O. viverrini infection, particularly those>50 years old, should be carefully monitored to prevent CCA. |
format | Online Article Text |
id | pubmed-10693972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Korean Society for Parasitology and Tropical Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-106939722023-12-04 Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand Prasopdee, Sattrachai Rojthongpond, Thittinan Chitkoolsamphan, Yanwadee Pholhelm, Montinee Yusuk, Siraphatsorn Pattaraarchachai, Junya Butthongkomvong, Kritiya Kulsantiwong, Jutharat Phanaksri, Teva Kunjantarachot, Anthicha Tesana, Smarn Sathavornmanee, Thanakrit Thitapakorn, Veerachai Parasites Hosts Dis Brief Communication This study aimed to identify the recent risk factors for Opisthorchis viverrini infection and cholangiocarcinoma (CCA) to improve disease prevention. The participants were divided into the following 3 groups based on their health status: healthy control (nonOV and nonCCA), those with O. viverrini infection (OV), and those with CCA. A questionnaire was used to explore their lifestyle and behaviors. Multivariate logistic regression and backward elimination were used to identify the significant risk factors. The results showed that the significant risk factors for both O. viverrini infection and CCA were age>50 years (odd ratio (OR)=8.44, P<0.001, 95% confidence intervals (CI) 2.98–23.90 and OR=43.47, P=0.001, 95% CI 14.71–128.45, respectively) and raw fish consumption (OR=8.48, P< 0.001, 95% CI 3.18–22.63 and OR=3.15, P=0.048, 95% CI 1.01–9.86, respectively). A history of O. viverrini infection was identified as an additional risk factor for CCA (OR=20.93, P=0.011, 95% CI 2.04–215.10). This study provided an update on the risk factors for O. viverrini infection and CCA. Asymptomatic patients with O. viverrini infection, particularly those>50 years old, should be carefully monitored to prevent CCA. The Korean Society for Parasitology and Tropical Medicine 2023-11 2023-11-28 /pmc/articles/PMC10693972/ /pubmed/38043542 http://dx.doi.org/10.3347/PHD.23032 Text en © 2023 The Korean Society for Parasitology and Tropical Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communication Prasopdee, Sattrachai Rojthongpond, Thittinan Chitkoolsamphan, Yanwadee Pholhelm, Montinee Yusuk, Siraphatsorn Pattaraarchachai, Junya Butthongkomvong, Kritiya Kulsantiwong, Jutharat Phanaksri, Teva Kunjantarachot, Anthicha Tesana, Smarn Sathavornmanee, Thanakrit Thitapakorn, Veerachai Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title | Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title_full | Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title_fullStr | Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title_full_unstemmed | Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title_short | Update on the risk factors for opisthorchiasis and cholangiocarcinoma in Thailand |
title_sort | update on the risk factors for opisthorchiasis and cholangiocarcinoma in thailand |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693972/ https://www.ncbi.nlm.nih.gov/pubmed/38043542 http://dx.doi.org/10.3347/PHD.23032 |
work_keys_str_mv | AT prasopdeesattrachai updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT rojthongpondthittinan updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT chitkoolsamphanyanwadee updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT pholhelmmontinee updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT yusuksiraphatsorn updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT pattaraarchachaijunya updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT butthongkomvongkritiya updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT kulsantiwongjutharat updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT phanaksriteva updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT kunjantarachotanthicha updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT tesanasmarn updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT sathavornmaneethanakrit updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand AT thitapakornveerachai updateontheriskfactorsforopisthorchiasisandcholangiocarcinomainthailand |