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Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study

OBJECTIVE: Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐...

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Autores principales: Ding, Xiaofang, Yuan, Yusong, Xu, Hailin, Jing, Zhengwei, Lu, Hao, Wang, Yuanli, Zhou, Junlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694016/
https://www.ncbi.nlm.nih.gov/pubmed/37814800
http://dx.doi.org/10.1111/os.13908
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author Ding, Xiaofang
Yuan, Yusong
Xu, Hailin
Jing, Zhengwei
Lu, Hao
Wang, Yuanli
Zhou, Junlin
author_facet Ding, Xiaofang
Yuan, Yusong
Xu, Hailin
Jing, Zhengwei
Lu, Hao
Wang, Yuanli
Zhou, Junlin
author_sort Ding, Xiaofang
collection PubMed
description OBJECTIVE: Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐hospital death in elderly patients with chronic ischemic diabetic foot after receiving TTT treatment. METHODS: A total of 54 patients were included in the study from January 1, 2017 to April 30, 2021, by being paired with the cases in case group with their demographic data and results of blood routine, liver and kidney function. There were nine patients in case group with six male and three male. Forty‐five patients were selected in control group according to gender and diabetes type with 30 male and 15 female. Single factor logics regression analysis was used to explore the risk factors and odd ratios (OR) of in‐hospital death in patients. The nomogram and decision curve analysis (DCA) had been done by R Studio software. RESULTS: The study found that age, course of diabetic foot, small dense low‐density Lipoprotein (smLDL), homocysteine (Hcy), superoxide dismutase (SOD), and prealbumin (PA) were risk factors for in‐hospital death of patients. The smLDL had the highest risk. The nomogram showed that PA accounted for the largest proportion in the death risk factors. The results of DCA proved that above six risk factors were the risk factors for patients with TEXAS Stage 3 and 4 diabetic foot ulcers. CONCLUSION: In the future diagnosis and TTT treatment for diabetic foot ulcers, doctors need to pay close attention to age, course of diabetic foot, smLDL, Hcy, SOD, and PA.
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spelling pubmed-106940162023-12-05 Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study Ding, Xiaofang Yuan, Yusong Xu, Hailin Jing, Zhengwei Lu, Hao Wang, Yuanli Zhou, Junlin Orthop Surg Research Articles OBJECTIVE: Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐hospital death in elderly patients with chronic ischemic diabetic foot after receiving TTT treatment. METHODS: A total of 54 patients were included in the study from January 1, 2017 to April 30, 2021, by being paired with the cases in case group with their demographic data and results of blood routine, liver and kidney function. There were nine patients in case group with six male and three male. Forty‐five patients were selected in control group according to gender and diabetes type with 30 male and 15 female. Single factor logics regression analysis was used to explore the risk factors and odd ratios (OR) of in‐hospital death in patients. The nomogram and decision curve analysis (DCA) had been done by R Studio software. RESULTS: The study found that age, course of diabetic foot, small dense low‐density Lipoprotein (smLDL), homocysteine (Hcy), superoxide dismutase (SOD), and prealbumin (PA) were risk factors for in‐hospital death of patients. The smLDL had the highest risk. The nomogram showed that PA accounted for the largest proportion in the death risk factors. The results of DCA proved that above six risk factors were the risk factors for patients with TEXAS Stage 3 and 4 diabetic foot ulcers. CONCLUSION: In the future diagnosis and TTT treatment for diabetic foot ulcers, doctors need to pay close attention to age, course of diabetic foot, smLDL, Hcy, SOD, and PA. John Wiley & Sons Australia, Ltd 2023-10-10 /pmc/articles/PMC10694016/ /pubmed/37814800 http://dx.doi.org/10.1111/os.13908 Text en © 2023 The Authors. Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Ding, Xiaofang
Yuan, Yusong
Xu, Hailin
Jing, Zhengwei
Lu, Hao
Wang, Yuanli
Zhou, Junlin
Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_full Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_fullStr Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_full_unstemmed Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_short Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_sort analysis of risk factors for in‐hospital death in elderly patients with texas stage 3 and 4 diabetic foot ulcers after tibial transverse translation: a case–control study
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694016/
https://www.ncbi.nlm.nih.gov/pubmed/37814800
http://dx.doi.org/10.1111/os.13908
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