Cargando…

Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases

OBJECTIVE: Intertrochanteric fracture is a very common but serious type of hip fracture in nonagenarians. The surgical treatment remains a significant challenge for orthopedists. The objective of this study was to investigate postoperative complications and survival outcomes compared between bipolar...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Xingchen, Gou, Wenlong, Wu, Siyu, Wang, Yu, Wang, Ziming, Xiong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694023/
https://www.ncbi.nlm.nih.gov/pubmed/37880497
http://dx.doi.org/10.1111/os.13913
_version_ 1785153286011092992
author Lu, Xingchen
Gou, Wenlong
Wu, Siyu
Wang, Yu
Wang, Ziming
Xiong, Yan
author_facet Lu, Xingchen
Gou, Wenlong
Wu, Siyu
Wang, Yu
Wang, Ziming
Xiong, Yan
author_sort Lu, Xingchen
collection PubMed
description OBJECTIVE: Intertrochanteric fracture is a very common but serious type of hip fracture in nonagenarians. The surgical treatment remains a significant challenge for orthopedists. The objective of this study was to investigate postoperative complications and survival outcomes compared between bipolar hemiarthroplasty (HA) and proximal femoral nail anti‐rotation (PFNA) in nonagenarians with intertrochanteric fractures, and to evaluate the efficacy and safety of the two surgical procedures in this patient population. METHODS: A total of 113 consecutive nonagenarians who underwent bipolar HA or PFNA for the treatment of intertrochanteric fractures from January 2006 to August 2021 were retrospectively studied in the current paper. There were 34 males and 79 females, with a mean age of 92.2 years (range 90–101 years) at the time of operation. The average duration of follow‐up was 29.7 months (range 1–120 months). The full cohort was divided into bipolar HA (77 cases) and PFNA (36 cases) groups. Damage control orthopedics was used to determine the optimal surgery time and assist in perioperative management. A restrictive blood transfusion strategy was employed, along with appropriate adjustments under multidisciplinary assessment, throughout the perioperative period. Perioperative clinical information and prognostic data were analyzed. Kaplan–Meier survival curves were used for survival analysis, and landmark analysis divided the entire follow‐up period into 1–12 months (short‐term), 13–42 months (medium‐term) and 43–120 months (long‐term) according to the configurations of Kaplan–Meier survival curves. RESULTS: Both groups had similar general variables except for the proportion of high adjusted Charlson comorbidity index (aCCI) (≥6 points) (6.5% in bipolar HA group and 22.2% in PFNA group, p = 0.024). Intraoperative blood loss and transfusion requirements were greater, and the intraoperative transfusion rates were higher in the bipolar HA group compared to the PFNA group (all p < 0.05). The complications rates, 1‐ to 60‐month cumulative all‐cause mortality, postoperative optimal Harris hip score (HHS), and Barthel index (BI) presented no significant difference between the two groups (all p > 0.05). Both groups had similar overall survival curves (p = 0.37). However, landmark analysis revealed that bipolar HA group exhibited higher survival rates in medium‐term (p = 0.01), while similar survival rates were observed in the short‐ and long‐term post‐operation periods (both p > 0.05). Cox regression with survival‐time‐dependent covariate calculated the hazard ratio (HR) of bipolar HA was 0.41 in medium‐term (p = 0.039). CONCLUSION: Bipolar HA is equally effective and reliable as PFNA for treating intertrochanteric fractures in nonagenarians. Despite resulting in more intraoperative blood loss and transfusions, bipolar HA therapy is associated with a higher medium‐term survival rate compared to PFNA treatment. The application of damage control orthopedics and precise perioperative patient blood management could contribute to the positive clinical outcomes observed in this patient population.
format Online
Article
Text
id pubmed-10694023
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley & Sons Australia, Ltd
record_format MEDLINE/PubMed
spelling pubmed-106940232023-12-05 Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases Lu, Xingchen Gou, Wenlong Wu, Siyu Wang, Yu Wang, Ziming Xiong, Yan Orthop Surg Clinical Articles OBJECTIVE: Intertrochanteric fracture is a very common but serious type of hip fracture in nonagenarians. The surgical treatment remains a significant challenge for orthopedists. The objective of this study was to investigate postoperative complications and survival outcomes compared between bipolar hemiarthroplasty (HA) and proximal femoral nail anti‐rotation (PFNA) in nonagenarians with intertrochanteric fractures, and to evaluate the efficacy and safety of the two surgical procedures in this patient population. METHODS: A total of 113 consecutive nonagenarians who underwent bipolar HA or PFNA for the treatment of intertrochanteric fractures from January 2006 to August 2021 were retrospectively studied in the current paper. There were 34 males and 79 females, with a mean age of 92.2 years (range 90–101 years) at the time of operation. The average duration of follow‐up was 29.7 months (range 1–120 months). The full cohort was divided into bipolar HA (77 cases) and PFNA (36 cases) groups. Damage control orthopedics was used to determine the optimal surgery time and assist in perioperative management. A restrictive blood transfusion strategy was employed, along with appropriate adjustments under multidisciplinary assessment, throughout the perioperative period. Perioperative clinical information and prognostic data were analyzed. Kaplan–Meier survival curves were used for survival analysis, and landmark analysis divided the entire follow‐up period into 1–12 months (short‐term), 13–42 months (medium‐term) and 43–120 months (long‐term) according to the configurations of Kaplan–Meier survival curves. RESULTS: Both groups had similar general variables except for the proportion of high adjusted Charlson comorbidity index (aCCI) (≥6 points) (6.5% in bipolar HA group and 22.2% in PFNA group, p = 0.024). Intraoperative blood loss and transfusion requirements were greater, and the intraoperative transfusion rates were higher in the bipolar HA group compared to the PFNA group (all p < 0.05). The complications rates, 1‐ to 60‐month cumulative all‐cause mortality, postoperative optimal Harris hip score (HHS), and Barthel index (BI) presented no significant difference between the two groups (all p > 0.05). Both groups had similar overall survival curves (p = 0.37). However, landmark analysis revealed that bipolar HA group exhibited higher survival rates in medium‐term (p = 0.01), while similar survival rates were observed in the short‐ and long‐term post‐operation periods (both p > 0.05). Cox regression with survival‐time‐dependent covariate calculated the hazard ratio (HR) of bipolar HA was 0.41 in medium‐term (p = 0.039). CONCLUSION: Bipolar HA is equally effective and reliable as PFNA for treating intertrochanteric fractures in nonagenarians. Despite resulting in more intraoperative blood loss and transfusions, bipolar HA therapy is associated with a higher medium‐term survival rate compared to PFNA treatment. The application of damage control orthopedics and precise perioperative patient blood management could contribute to the positive clinical outcomes observed in this patient population. John Wiley & Sons Australia, Ltd 2023-10-25 /pmc/articles/PMC10694023/ /pubmed/37880497 http://dx.doi.org/10.1111/os.13913 Text en © 2023 The Authors. Orthopaedic Surgery published by Tianjin Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Articles
Lu, Xingchen
Gou, Wenlong
Wu, Siyu
Wang, Yu
Wang, Ziming
Xiong, Yan
Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title_full Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title_fullStr Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title_full_unstemmed Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title_short Complication Rates and Survival of Nonagenarians after Hip Hemiarthroplasty versus Proximal Femoral Nail Antirotation for Intertrochanteric Fractures: A 15‐Year Retrospective Cohort Study of 113 Cases
title_sort complication rates and survival of nonagenarians after hip hemiarthroplasty versus proximal femoral nail antirotation for intertrochanteric fractures: a 15‐year retrospective cohort study of 113 cases
topic Clinical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694023/
https://www.ncbi.nlm.nih.gov/pubmed/37880497
http://dx.doi.org/10.1111/os.13913
work_keys_str_mv AT luxingchen complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases
AT gouwenlong complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases
AT wusiyu complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases
AT wangyu complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases
AT wangziming complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases
AT xiongyan complicationratesandsurvivalofnonagenariansafterhiphemiarthroplastyversusproximalfemoralnailantirotationforintertrochantericfracturesa15yearretrospectivecohortstudyof113cases