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Structure-based identification of novel inhibitors targeting the enoyl-ACP reductase enzyme of Acinetobacter baumannii

Acinetobacter baumannii is a Gram-negative multidrug-resistant bacterial pathogen primarily associated with nosocomial infections resulting in increased morbidity and mortality in adults and infants, especially in sub-Saharan Africa where the clinical burden is high. New therapeutics are needed to t...

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Detalles Bibliográficos
Autores principales: Khan, Shama, Madhi, Shabir A., Olwagen, Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694131/
https://www.ncbi.nlm.nih.gov/pubmed/38044353
http://dx.doi.org/10.1038/s41598-023-48696-z