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Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis

BACKGROUND: Age and sex are prominent risk factors for heart failure and determinants of structural and functional changes of the heart. Cardiac fibroblasts (cFB) are beyond their task as extracellular matrix-producing cells further recognized as inflammation-supporting cells. The present study aime...

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Detalles Bibliográficos
Autores principales: Pappritz, Kathleen, Puhl, Sarah-Lena, Matz, Isabel, Brauer, Erik, Shia, Yi Xuan, El-Shafeey, Muhammad, Koch, Suzanne E., Miteva, Kapka, Mucha, Christin, Duda, Georg N., Petersen, Ansgar, Steffens, Sabine, Tschöpe, Carsten, Van Linthout, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694208/
http://dx.doi.org/10.3389/fcvm.2023.1117419