Development and validation of a disulfidptosis-related scoring system to predict clinical outcome and immunotherapy response in acute myeloid leukemia by integrated analysis of single-cell and bulk RNA-sequencing

Background: Disulfidptosis is a metabolically relevant mode of cell death, and its relationship with acute myeloid leukemia (AML) has not been clarified. In this study, disulfidptosis scores were computed to examine the potential biological mechanisms. Methods: Consensus clustering was applied to de...

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Detalles Bibliográficos
Autores principales: Zhong, Fangmin, Jiang, Junyao, Yao, Fang-Yi, Liu, Jing, Shuai, Xu, Wang, Xin-Lu, Huang, Bo, Wang, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694296/
http://dx.doi.org/10.3389/fphar.2023.1272701

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