CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB pathway

C-X-C chemokine receptor type 4 (CXCR4) is critical for homeostasis of the adaptive and innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential kinase that regulates inflammation in immune cells through multiple signaling pathways. This study aims to explore th...

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Detalles Bibliográficos
Autores principales: Liu, Chengli, Yao, Kun, Tian, Qi, Guo, Yujia, Wang, Guijun, He, Peibang, Wang, Jianfeng, Wang, Jian, Zhang, Zhan, Li, Mingchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694315/
https://www.ncbi.nlm.nih.gov/pubmed/37979447
http://dx.doi.org/10.1016/j.redox.2023.102960

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