Differentiation between lung allograft rejection and infection using donor-derived cell-free DNA and pathogen detection by metagenomic next-generation sequencing

BACKGROUND: In lung transplant recipients (LTRs), the primary causes of mortality are rejection and infection, which often present similar symptoms, making differentiation challenging. This study aimed to explore the diagnostic efficacy of plasma donor-derived cell-free DNA (dd-cfDNA) in conjunction...

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Detalles Bibliográficos
Autores principales: Ju, Chunrong, Wang, Lulin, Xu, Peihang, Wang, Xiaohua, Xiang, Dong, Xu, Yu, Xu, Xin, Chen, Rongchang, He, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694331/
http://dx.doi.org/10.1016/j.heliyon.2023.e22274

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