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Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease

Neuropsychiatric symptoms and syndromes are among the most common non-motor symptoms of Parkinson's Disease but they are frequently unrecognized and untreated. Dopamine Dysregulation Syndrome is an uncommon complication of the treatment of Parkinson's disease, characterized by an addictive...

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Autores principales: Silva, Carlos, Rebelo, Marta, Chendo, Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694353/
http://dx.doi.org/10.3389/fneur.2023.1290653
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author Silva, Carlos
Rebelo, Marta
Chendo, Inês
author_facet Silva, Carlos
Rebelo, Marta
Chendo, Inês
author_sort Silva, Carlos
collection PubMed
description Neuropsychiatric symptoms and syndromes are among the most common non-motor symptoms of Parkinson's Disease but they are frequently unrecognized and untreated. Dopamine Dysregulation Syndrome is an uncommon complication of the treatment of Parkinson's disease, characterized by an addictive use of dopamine far more than the dosage required for treatment of objective motor impairment, leading to severe dyskinesia, euphoria, aggressivity, or psychosis. We present a paradigmatic case of Dopamine Dysregulation Syndrome, Mania, and Compulsive Buying in a 55-year-old male with Parkinson's Disease. We also reviewed the risk factors and the therapeutic management of Dopamine Dysregulation Syndrome in Parkinson's Disease.
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spelling pubmed-106943532023-12-05 Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease Silva, Carlos Rebelo, Marta Chendo, Inês Front Neurol Neurology Neuropsychiatric symptoms and syndromes are among the most common non-motor symptoms of Parkinson's Disease but they are frequently unrecognized and untreated. Dopamine Dysregulation Syndrome is an uncommon complication of the treatment of Parkinson's disease, characterized by an addictive use of dopamine far more than the dosage required for treatment of objective motor impairment, leading to severe dyskinesia, euphoria, aggressivity, or psychosis. We present a paradigmatic case of Dopamine Dysregulation Syndrome, Mania, and Compulsive Buying in a 55-year-old male with Parkinson's Disease. We also reviewed the risk factors and the therapeutic management of Dopamine Dysregulation Syndrome in Parkinson's Disease. Frontiers Media S.A. 2023-11-20 /pmc/articles/PMC10694353/ http://dx.doi.org/10.3389/fneur.2023.1290653 Text en Copyright © 2023 Silva, Rebelo and Chendo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Silva, Carlos
Rebelo, Marta
Chendo, Inês
Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title_full Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title_fullStr Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title_full_unstemmed Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title_short Case report: Dopamine Dysregulation Syndrome, mania, and compulsive buying in a patient with Parkinson's disease
title_sort case report: dopamine dysregulation syndrome, mania, and compulsive buying in a patient with parkinson's disease
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694353/
http://dx.doi.org/10.3389/fneur.2023.1290653
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