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The testicular microvasculature in Klinefelter syndrome is immature with compromised integrity and characterized by excessive inflammatory cross-talk

STUDY QUESTION: Does Klinefelter syndrome (KS) lead to a distinct gene expression pattern at single-cell level in the testes that could provide insight into the reported microvascular dysfunction in the testes? SUMMARY ANSWER: A distinct gene expression pattern within microvascular-associated cells...

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Detalles Bibliográficos
Autores principales: Johannsen, Emma B, Skakkebæk, Anne, Kalucka, Joanna M, Fedder, Jens, Gravholt, Claus H, Just, Jesper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694403/
https://www.ncbi.nlm.nih.gov/pubmed/37910660
http://dx.doi.org/10.1093/humrep/dead224