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Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation

STUDY QUESTION: Can in vitro maturation (IVM) and developmental competence of human oocytes be improved by co-culture with ovarian support cells (OSCs) derived from human-induced pluripotent stem cells (hiPSCs)? SUMMARY ANSWER: OSC-IVM significantly improves the rates of metaphase II (MII) formation...

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Detalles Bibliográficos
Autores principales: Piechota, Sabrina, Marchante, Maria, Giovannini, Alexa, Paulsen, Bruna, Potts, Kathryn S, Rockwell, Graham, Aschenberger, Caroline, Noblett, Alexander D, Figueroa, Alexandra B, Sanchez, Marta, Barrachina, Ferran, Wiemer, Klaus, Guzman, Luis, Belchin, Pedro, Pierson Smela, Merrick, Fortuna, Patrick R J, Chatterjee, Pranam, Tran, Nam D, Kelk, Dawn A, Forti, Marcy, Marcinyshyn, Shelby, Smith, Trozalla, McCulloh, David H, Fernandez-Gonzalez, Marta-Julia, Abittan, Baruch, Ortiz, Silvia, Klein, Joshua U, Klatsky, Peter, Ordonez-Perez, Daniel, Kramme, Christian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694404/
https://www.ncbi.nlm.nih.gov/pubmed/37815487
http://dx.doi.org/10.1093/humrep/dead205