Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-β

To better implement mesenchymal stem cell (MSC)-based therapy toward cartilage diseases, a more efficient and less off-target chondrogenesis protocol is needed. Here, we present a protocol to induce human MSC chondrogenesis via Wnt antagonism. We describe steps for pellet formation, Wnt antagonism-b...

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Detalles Bibliográficos
Autores principales: Hsieh, Chen-Chan, Chang, Chia-Chi, Hsu, Pei-Ju, Chen, Linyi, Yen, B. Linju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694580/
https://www.ncbi.nlm.nih.gov/pubmed/37979177
http://dx.doi.org/10.1016/j.xpro.2023.102728

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